Can someone who was deported some 20 plus years ago can be petition to re-enter the U.S.A. by his U.S. Citizen wife. The reason for the deportation was due to drug related felonies charges.
You can petition but based on the limited information you've provided, it does not look like he will be re-entering. You mentioned drug-related felony charges, which is somewhat vague, so it might be better to provide more information so you can get a better and clearer answer.