DUI and EB2 green card immigration process?

As my colleague notes, the DUI will be disclosed as part of the I-485 green card process. Depending on how recent the DUI is, you should consider having the judgment of conviction set aside by the court before applying to adjust status. This will help demonstrate your good moral character. Best of luck!

The PERM and I-140 are employer applications - so there is no issue with your DUI. That will be raised during your I-485 application, and should you apply for a visa from a U.S. Consulate before then as well.

You have been given great advice but going it alone with immigration is not a good idea. You need to hire a local experienced immigration attorney.